다양한 이종치아 골이식재를 이용한 두개골 결손부 수복: 동물 연구
Restoration of Calvarial Defect Using a Variety of Xenogenous Tooth Bone Graft Material: Animal Study
김영균, 김종화, 윤필영, 황지연, 엄인웅, 정동준,
소속 상세정보
김영균 ( Kim Young-Kyun ) - 분당서울대학교병원 치과 구강악안면외과
김종화 ( Kim Jong-Hwa ) - 분당서울대학교병원 치과 구강악안면외과
윤필영 ( Yun Pil-Young ) - 분당서울대학교병원 치과 구강악안면외과
황지연 ( Hwang Ji-Yeon ) - 분당서울대학교병원 전임상실험센터
엄인웅 ( Um In-Woong ) - 한국치아은행 연구개발기관
정동준 ( Jung Dong-Jun ) - 순천향대학교 의과대학 병리학교실
KMID : 0360120120340050299
Abstract
Purpose: The purpose of this study was to evaluate the histological healing process of 3 different types of xenogenic tooth bone graft material and xenogenic bone graft material.
Methods: Three types of human tooth bone graft material (chips, crowns, and roots) and BioOss (Geistlich Pharma AG, Wolhausen, Switzerland) was filled at the preformed 4 round-shaped calvarial bone defects of beagle dogs. The beagles were sacrificed at 2, 4, 8, and 12 weeks, respectively, for radiological and histological evaluation.
Results: Increased strength and radiopacity were detected in all graft material groups in time-dependent manner. New bone was formed and matured surrounding the graft material histologically. Also, a new bone was directly integrated with graft material.
Conclusion: It was expected that newly developed tooth bone graft material would show good bone healing capacity if it was used as a graft material for the restoration of bony defect.
키워드
Xenogenic;Tooth;Bone graft
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